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Expert-led conference insights in malignant and non-malignant hematology
Expert interview

FLIGHT trial: Mycophenolate plus steroid a possible first-line option for ITP

Maria Lozano comments on the trial showing the benefits of combining mycophenolate with corticosteroid in the first-line setting and outlines what this might mean for early intensive therapy in immune thrombocytopenia.
Published: 14th December 2020
Photo of Maria Lozano
Speaker: Maria Lozano
Speaker Affiliation: University of Murcia, Spain

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Professor Jane Apperley and colleagues discuss the latest data in CML

Date & Time:
17th December 9:30-10:30am (CET)
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Prof. Jane Apperley (UK) chairs an expert panel to discuss the key data and findings from the CML scientific sessions at the 62nd ASH Annual Meeting. Register now to secure your place.
Disease area: CML
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Professor John Gribben and colleagues discuss the latest data in MDS and AML

Date & Time:
16th December 3-4pm (CET)
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Prof. John Gribben (UK) chairs an expert panel to discuss the key data and findings from the MDS/AML scientific sessions at the 62nd ASH Annual Meeting. Register now to secure your place.
Disease area: MDS/AML
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Professor Martin Dreyling and colleagues discuss the latest data in FL, DLBCL and MCL

Date & Time:
14th December 11am-12pm (CET)
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Prof. Martin Dreyling (Germany) chairs an expert panel to discuss the key data and findings from the FL/DLBCL/MCL scientific sessions at the 62nd ASH Annual Meeting. Register now to secure your place.
Disease area: FL/DLBCL/MCL
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ASH 2020 Podcast Collection: GvHD

Published:
30th March 2021
Speaker: Jacopo Mariotti
Speaker Affiliation: Bone Marrow Transplantation Unit, Humanitas Research Hospital, Milan, Italy
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Dr. Jacopo Mariotti discusses his top highlights of the data and findings from the GvHD scientific sessions at the ASH 2020.
Disease area: GvHD
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ASH 2020 Podcast Collection: MDS/AML

Published:
22nd March 2021
Speaker: António Almeida
Speaker Affiliation: Hospital da Luz, Lisbon, Portugal
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Professor António Almeida discusses his top highlights of the data and findings from the MDS/AML scientific sessions at the ASH 2020.
Disease area: MDS/AML
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ASH 2020 Podcast Collection: Sickle Cell Anemia

Published:
2nd March 2021
Speaker: Giovanna Russo & Raffaella Colombatti
Speaker Affiliation: Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy (GR); Department of Women’s and Children’s Health, University of Padova, Padova, Italy (RC)
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Professor Giovanna Russo and Professor Raffaella Colombatti discuss their top highlights of the data and findings from the Sickle cell scientific sessions at the ASH 2020.
Disease area: Sickle Cell
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ASH 2020 Podcast Collection: Immune Thrombocytopenia

Published:
13th March 2021
Speaker: Sabine Eichinger & Johanna Gebhart
Speaker Affiliation: Department of Medicine, Medical University of Vienna, Vienna, Austria (SE, JG)
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Dr. Sabine Eichinger and Dr. Johanna Gebhart discuss their top highlights of the data and findings from the ITP scientific sessions at the ASH 2020.
Disease area: ITP
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ASH 2020 Podcast Collection: FL/DLBCL

Published:
9th March 2021
Speaker: Christopher Paul Fox & Wendy Osborne
Speaker Affiliation: Nottingham University Hospitals NHS Trust, Nottingham, UK (CP); Freeman Hospital and Newcastle upon Tyne Hospital NHS Foundation Trust, Newcastle, UK (WO)
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Dr. Christopher Fox and Dr. Wendy Osborne discuss their top highlights of the data and findings from the FL/DLBCL scientific sessions focusing on CAR-T cell therapies at the ASH 2020.
Disease area: FL/DLBCL
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ASH 2020 Podcast Collection: MPN

Published:
13th March 2021
Speaker: Massimo Breccia
Speaker Affiliation: Department of Translational and Precision Medicine, University of Rome, Rome, Italy
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Dr. Massimo Breccia discusses his top highlights of the data and findings from the MPN scientific sessions at the ASH 2020.
Disease area: MPN
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ASH 2020 Podcast Collection: CML

Published:
15th March 2021
Speaker: Massimo Breccia
Speaker Affiliation: Department of Translational and Precision Medicine, University of Rome, Rome, Italy
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Dr. Massimo Breccia discusses his top highlights of the data and findings from the CML scientific sessions at the ASH 2020.
Disease area: CML
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Risk factors for intracranial hemorrhage in older ITP patients identified

Published:
February 3rd 2021
Speaker: Shreeya Nanda
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Chinese researchers have identified predictive and prognostic factors for intracranial hemorrhage in immune thrombocytopenia patients older than 60 years of age.
Disease area: ITP
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Sutimlimab elicits ‘sustained’ responses in some chronic ITP patients

Published:
February 3rd 2021
Speaker: Shreeya Nanda
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Extended follow-up of a phase 1b trial shows that responses to sutimlimab are maintained after more than a year of treatment in a subset of chronic immune thrombocytopenia patients with an inadequate response to multiple previous therapies.
Disease area: ITP
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Gian Luca Forni - Outcomes of COVID-19 in people with hemoglobinopathies reported

Published:
21st January 2021
Speaker: Gian Luca Forni
Speaker Affiliation: Ospedale Galliera, Genoa, Italy
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Gian Luca Forni shares data on the prevalence and outcomes of SARS-CoV-2 infection in Italian patients with thalassemia or sickle cell disease.
Disease area: Sickle Cell
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Radiotherapy plus cyclophosphamide–tacrolimus ‘feasible’ alloHCT regimen for AML

Published:
21st January 2021
Speaker: Lynda Williams
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A chemotherapy-free allogeneic hematopoietic transplantation regimen is feasible and could reduce the risk of graft-versus-host disease and relapse in patients with acute myeloid leukemia… (read more)
Disease area: GvHD
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Blood cell subpopulations show biomarker potential in pediatric chronic GvHD

Published:
21st January 2021
Speaker: Lucy Piper
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Identifying certain subpopulations of T and natural killer cells could help to diagnose pediatric chronic GvHD at the onset of the disorder… (read more)
Disease area: GvHD
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Rick Kapur - Understanding platelet count and bleeding outcomes in ITP

Published:
21st January 2021
Speaker: Rick Kapur
Speaker Affiliation: Sanquin Research, and Landsteiner Laboratory, Amsterdam, The Netherlands
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Rick Kapur offers insights on the findings of a literature review looking at variability in platelet count and bleeding outcomes in patients with immune thrombocytopenia and the need for standardization.
Disease area: ITP
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Rilzabrutinib achieves ‘durable response’ for heavily pretreated ITP patients

Published:
21st December 2020
Speaker: Lynda Williams
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Early results for the oral Bruton tyrosine kinase (BTK) inhibitor rilzabrutinib support its use in patients with relapsed or refractory immune thrombocytopenia (ITP). David Kuter, from Massachusetts... (read more)
Disease area: ITP
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Delphine Rea - CANDID study characterizes COVID-19 risk in CML patients

Published:
21st December 2020
Speaker: Delphine Rea
Speaker Affiliation: Hôpital Saint-Louis, Paris, France
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Delphine Rea presents the International Chronic Myeloid Leukemia Foundation’s CANDID study findings showing that age is the most significant risk factor for COVID-19 mortality in CML patients.
Disease area: MPN - CML
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Itacitinib plus CNI-based regimen shows potential for GvHD prevention after alloHCT

Published:
21st January 2021
Speaker: Lynda Williams
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Findings from a proof-of-principle study indicate that use of the JAK1 inhibitor itacitinib alongside a calcineurin inhibitor may help prevent GvHD after transplantation… (read more)
Disease area: GvHD
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Naranie Shanmuganathan - Cancer-related mutations linked to poor CML prognosis

Published:
3rd February 2021
Speaker: Naranie Shanmuganathan
Speaker Affiliation: Royal Adelaide Hospital, Australia
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Naranie Shanmuganathan describes the characterization of cancer-related mutations at time of first-line treatment initiation for chronic myeloid leukemia and their relationship to patient prognosis.
Disease area: MPN-CML
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Mohamad Mohty - ROCKstar: Belumosudil shows potential for refractory, advanced GvHD

Published:
16th December 2020
Speaker: Mohamad Mohty
Speaker Affiliation: Hôpital Saint-Antoine, Paris, France
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Mohamad Mohty highlights the findings from the ROCKstar study showing a good response to belumosudil among heavily pretreated patients with chronic graft-versus-host disease.
Disease area: GvHD
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Selim Corbacioglu - CRISPR-Cas9 gene editing shows sickle cell disease promise

Published:
16th December 2020
Speaker: Selim Corbacioglu
Speaker Affiliation: University of Regensburg, Germany
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Selim Corbacioglu discusses the CLIMB SCD-121 and CLIMB THAL-111 trials demonstrating the potential of CTX001, a novel CRISPR-Cas9 gene editing therapy, for the treatment of sickle cell disease and transfusion-dependent beta-thalassemia, respectively.
Disease area: Sickle Cell
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Shehu Umar Abdullahi - SPRINT supports low-dose hydroxyurea for secondary stroke prevention in SCD

Published:
14th December 2020
Speaker: Shehu Umar Abdullahi
Speaker Affiliation: Bayero University/Aminu Kano Teaching hospital, Kano, Nigeria
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Shehu Umar Abdullahi takes us through the SPRINT study establishing fixed low-dose hydroxyurea with biannual complete blood counts as an appropriate strategy in low-income settings for preventing secondary strokes in children with sickle cell disease.
Disease area: Sickle Cell
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Françoise Bernaudin - Study sheds light on intra- and extracranial arteriopathy in sickle cell disease

Published:
14th December 2020
Speaker: Françoise Bernaudin
Speaker Affiliation: CHIC Hospital, Créteil, France
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Françoise Bernaudin reports on their research evaluating the incidence of intra- and extracranial cerebral arteriopathy, and associated risk factors, in a longitudinal, pediatric sickle cell disease cohort.
Disease area: Sickle Cell

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